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"Simple and effective: throw it, everything is clean."
The standard Grenade is low-tier Equipment (acquired after unlocking the Skill of the same name) which can be used in one of three equipment slots available per Trooper. Upon impact, it explodes with an Area of Effect covering 2x2, causing 6-12 Damage initially and Fall Damage as a bonus.
Also, troopers can kill themselves of their friends with their own grenade due to its low accuracy.
The grenade can deal high Damage, killing weaker troopers. Troopers who survive may need time to get back to their feet and reacquire their targets. It is a very useful weapon, but isn't entirely accurate when thrown unless the trooper has the skill King of Boules.
As with all explosives, grenades don't hurt the target's limbs or vital organs directly, dealing Damage generally instead. Nevertheless, weapons carried by the victims can still be occasionally dropped if the target does not have Death Grip.